Abrignani Sergio

Chief Scientific Officer

SARS vaccine protective in mice.
Stadler K, Roberts A, Becker S, Vogel L, Eickmann M, Kolesnikova L, Klenk HD, Murphy B, Rappuoli R, Abrignani S, Subbarao K.
Emerg Infect Dis. 2005 Aug;11(8):1312-4

Prospects for a vaccine against the hepatitis C virus.
Houghton M, Abrignani S.
Nature. 2005 Aug 18;436(7053):961-6. Review.

Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells.
Capo S, Nuti S, Scarselli M, Tavarini S, Montigiani S, Mori E, Finco O, Abrignani S, Grandi G, Bensi G.
Vaccine. 2005 Oct 10;23(42):5028-37. Erratum in: Vaccine. 2007 Apr 30;25(17):3516.

Folding and dimerization of hepatitis C virus E1 and E2 glycoproteins in stably transfected CHO cells.
Brazzoli M, Helenius A, Foung SK, Houghton M, Abrignani S, Merola M.
Virology. 2005 Feb 5;332(1):438-53.

Comparable functions of plasmacytoid and monocyte-derived dendritic cells in chronic hepatitis C patients and healthy donors.
Piccioli D, Tavarini S, Nuti S, Colombatto P, Brunetto M, Bonino F, Ciccorossi P, Zorat F, Pozzato G, Comar C, Abrignani S, Wack A.
J Hepatol. 2005 Jan;42(1):61-7.

Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells.
Mazzocca A, Sciammetta SC, Carloni V, Cosmi L, Annunziato F, Harada T, Abrignani S, Pinzani M.
J Biol Chem. 2005 Mar 25;280(12):11329-39.

Sexual transmission of hepatitis C virus and prevention with intramuscular immunoglobulin.
Piazza M, Sagliocca L, Tosone G, Guadagnino V, Stazi MA, Orlando R, Borgia G, Rosa D, Abrignani S, Palumbo F, Manzin A, Clementi M.
AIDS Patient Care STDS. 1998 Aug;12(8):611-8.

Association of hepatitis C virus envelope proteins with exosomes.
Masciopinto F, Giovani C, Campagnoli S, Galli-Stampino L, Colombatto P, Brunetto M, Yen TS, Houghton M, Pileri P, Abrignani S.
Eur J Immunol. 2004 Oct;34(10):2834-42.

Synthesis and characterization of a native, oligomeric form of recombinant severe acute respiratory syndrome coronavirus spike glycoprotein.
Song HC, Seo MY, Stadler K, Yoo BJ, Choo QL, Coates SR, Uematsu Y, Harada T, Greer CE, Polo JM, Pileri P, Eickmann M, Rappuoli R, Abrignani S, Houghton M, Han JH.
J Virol. 2004 Oct;78(19):10328-35.

Production of profibrotic cytokines by invariant NKT cells characterizes cirrhosis progression in chronic viral hepatitis.
de Lalla C, Galli G, Aldrighetti L, Romeo R, Mariani M, Monno A, Nuti S, Colombo M, Callea F, Porcelli SA, Panina-Bordignon P, Abrignani S, Casorati G, Dellabona P.
J Immunol. 2004 Jul 15;173(2):1417-25.

Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection.
Accapezzato D, Francavilla V, Paroli M, Casciaro M, Chircu LV, Cividini A, Abrignani S, Mondelli MU, Barnaba V.
J Clin Invest. 2004 Apr;113(7):963-72.

SARS–beginning to understand a new virus.
Stadler K, Masignani V, Eickmann M, Becker S, Abrignani S, Klenk HD, Rappuoli R.
Nat Rev Microbiol. 2003 Dec;1(3):209-18. Review.

Molecular analysis of V(H)I+ B lymphocytes in hepatitis C patients.
Galli-Stampino L, Pasqualini A, Pozzato G, Bonino F, Filipponi F, Mosca M, Masciopinto F, Abrignani S, Uematsu Y.
Dig Liver Dis. 2003 Nov;35(11):788-94.

Phylogeny of the SARS coronavirus.
Eickmann M, Becker S, Klenk HD, Doerr HW, Stadler K, Censini S, Guidotti S, Masignani V, Scarselli M, Mora M, Donati C, Han JH, Song HC, Abrignani S, Covacci A, Rappuoli R.
Science. 2003 Nov 28;302(5650):1504-5.

Innate immune responses support adaptive immunity: NKT cells induce B cell activation.
Galli G, Nuti S, Tavarini S, Galli-Stampino L, De Lalla C, Casorati G, Dellabona P, Abrignani S.
Vaccine. 2003 Jun 1;21 Suppl 2:S48-54. Review.

INGM researches are supported by