Abrignani Sergio

Chief Scientific Officer

Sexual transmission of the hepatitis C virus and efficacy of prophylaxis with intramuscular immune serum globulin. A randomized controlled trial.
Piazza M, Sagliocca L, Tosone G, Guadagnino V, Stazi MA, Orlando R, Borgia G, Rosa D, Abrignani S, Palumbo F, Manzin A, Clementi M.
Arch Intern Med. 1997 Jul 28;157(14):1537-44.

Induction of CD4+ T cell depletion in mice doubly transgenic for HIV gp120 and human CD4.
Finco O, Nuti S, De Magistris MT, Mangiavacchi L, Aiuti A, Forte P, Fantoni A, van der Putten H, Abrignani S.
Eur J Immunol. 1997 Jun;27(6):1319-24.

Bystander activation by cytokines of intrahepatic T cells in chronic viral hepatitis.
Abrignani S.
Semin Liver Dis. 1997;17(4):319-22. Review.

Immune responses throughout hepatitis C virus (HCV) infection: HCV from the immune system point of view.
Abrignani S.
Springer Semin Immunopathol. 1997;19(1):47-55. Review.

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.
Rosa D, Campagnoli S, Moretto C, Guenzi E, Cousens L, Chin M, Dong C, Weiner AJ, Lau JY, Choo QL, Chien D, Pileri P, Houghton M, Abrignani S.
Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1759-63.

Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant.
Di Tommaso A, Saletti G, Pizza M, Rappuoli R, Dougan G, Abrignani S, Douce G, De Magistris MT.
Infect Immun. 1996 Mar;64(3):974-9.

Human naive T cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T cells.
Unutmaz D, Baldoni F, Abrignani S.
Int Immunol. 1995 Sep;7(9):1417-24.

Cellular immune reactions against hepatitis C core in chronic hepatitis C.
Abrignani S.
Gastroenterology. 1995 Jun;108(6):1957-8.

Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies.
Di Tommaso A, Xiang Z, Bugnoli M, Pileri P, Figura N, Bayeli PF, Rappuoli R, Abrignani S, De Magistris MT.
Infect Immun. 1995 Mar;63(3):1102-6.

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.
Unutmaz D, Pileri P, Abrignani S.
J Exp Med. 1994 Sep 1;180(3):1159-64.

Formaldehyde treatment of proteins can constrain presentation to T cells by limiting antigen processing.
di Tommaso A, de Magistris MT, Bugnoli M, Marsili I, Rappuoli R, Abrignani S.
Infect Immun. 1994 May;62(5):1830-4.

Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C.
Minutello MA, Pileri P, Unutmaz D, Censini S, Kuo G, Houghton M, Brunetto MR, Bonino F, Abrignani S.
J Exp Med. 1993 Jul 1;178(1):17-25.

N-glycosylation of HIV-gp120 may constrain recognition by T lymphocytes.
Botarelli P, Houlden BA, Haigwood NL, Servis C, Montagna D, Abrignani S.
J Immunol. 1991 Nov 1;147(9):3128-32.

Safety and immunogenicity of a genetically engineered human immunodeficiency virus vaccine.
Wintsch J, Chaignat CL, Braun DG, Jeannet M, Stalder H, Abrignani S, Montagna D, Clavijo F, Moret P, Dayer JM, et al.
J Infect Dis. 1991 Feb;163(2):219-25.

Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.
Abrignani S, Montagna D, Jeannet M, Wintsch J, Haigwood NL, Shuster JR, Steimer KS, Cruchaud A, Staehelin T.
Proc Natl Acad Sci U S A. 1990 Aug;87(16):6136-40.

INGM researches are supported by