Publications 2014

Plasticity of human CD4 T cell subsets.
Geginat J, Paroni M, Maglie S, Alfen JS, Kastirr I, Gruarin P, DeSimone M, Pagani M, Abrignani.
Front.Immunol. 2014 Dec 16;5:630.

eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression.
Brina D, Miluzio A, Ricciardi S, Biffo S.
Biochim Biophys Acta. 2014 Sep 22. pii: S1874-9399(14)00252-1

NS5A inhibitors impair NS5A- PI4KIIIα complex formation and cause a decrease of PI4P and cholesterol levels in HCV-associated membranes.
Reghellin V, Donnici L, Fenu S, Berno V, Calabrese V, Pagani M, Abrignani S, Peri F, De Francesco R, Neddermann P.
Antimicrob Agents Chemother. 2014 Dec;58(12):7128-40.

Daclatasvir: a team player rather than a prima donna in the treatment of hepatitis C.
Aghemo A, De Francesco R.
Gut. 2014 Sep 5. pii: gutjnl-2014-307958. doi: 10.1136/ [Epub ahead of print]

Photodynamic antibacterial and antibiofilm activity of RLP068/Cl against Staphylococcus aureus and Pseudomonas aeruginosa forming biofilms on prosthetic material
Vassena, C., Fenu, S., Giuliani, F., Fantetti, L., Roncucci, G., Simonutti, G., Romano, C. L., De Francesco, R., and Drago, L.
Int J Antimicrob Agents 2014; 44: 47-55

Repetitive Elements dynamics in cell identity programming, maintenance and disease
Bodega B., Orlando V.
Current Opinion in Cell Biology, 2014; 31: 67-73.

Interaction between PNPLA3 I148M Variant and Age at Infection in Determining Fibrosis Progression in Chronic Hepatitis C.
De Nicola S, Dongiovanni P, Aghemo A, Cheroni C, D’Ambrosio R, Pedrazzini M, Marabita F, Donnici L, Maggioni M, Fargion S, Colombo M, De Francesco R, Valenti L
PLoS One 2014; 9(8):e106022.

IL-21 Is a Central Memory T Cell-Associated Cytokine That Inhibits the Generation of Pathogenic Th1/17 Effector Cells.
Kastirr I, Maglie S, Paroni M, Alfen JS, Nizzoli G, Sugliano E, Crosti MC, Moro M, Steckel B, Steinfelder S, Stölzel K, Romagnani C, Botti F, Caprioli F, Pagani M, Abrignani S, Geginat J
J Immunol. 2014 Oct 1;193(7):3322-31. 

In vitro antibiofilm activity of bioactive glass S53P4.
Drago L, Vassena C, Fenu S, Vecchi ED, Signori V, Francesco RD, Romanò CL.
Future Microbiol 2014; 9:593-601.

The characterization of a novel monoclonal antibody against CD93 unveils a new antiangiogenic target.
Orlandini M, Galvagni F, Bardelli M, Rocchigiani M, Lentucci C, Anselmi F, Zippo A, Bini L, Oliviero S.
Oncotarget. 2014 May 15;5(9):2750-60.

iNKT cell help to B cells: a cooperative job between innate and adaptive immune responses
P Dellabona, S Abrignani, G Casorati
Eur J Immunol, 2014 Aug;44(8):2230-7.

The Association of Il28b Genotype with the Histological Features of Chronic Hepatitis C Is HCV Genotype Dependent
D’Ambrosio R, Aghemo A, De Francesco R, Rumi MG, Galmozzi E, De Nicola S, Cheroni C, Clark PJ,Ronchi G, Lampertico P, Colombo M.
Int. J. Mol. Sci. 2014, 15(5), 7213-7224

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors
McGivern D, Masaki T, Williford S, Ingravallo P, Feng Z, Lahser F, Asante-Appiah E, Neddermann P, De Francesco R, Howe A, Lemon S.
Gastroenterlogy, 2014 Aug;147(2):453-62.

Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis.
Selmi C, Cavaciocchi F, Lleo A, Cheroni C, De Francesco R, Lombardi S, De Santis M, Meda F, Raimondo MG, Crotti C, Folci M, Zammataro L, Mayo MJ, Bach N, Shimoda S, Gordon SC, Miozzo M, Invernizzi P, Podda M, Scavelli R, Martin MR, Lasalle JM, Gershwin ME.
Front Immunol. 2014 Mar 28;5:128

Interleukin 28B genotype and insulin resistance in chronic hepatitis C patients
Degasperi E, Valenti L, Aghemo A, De Francesco R, Rumi M, Soffredini R, Donnici L, Cheroni C, Fargion S, Zanoni V, Orsi E, Colombo M.
Antivir Ther. 2014;19(8):747-53.

Oxysterol-Binding Protein is a Phosphatidylinositol 4-kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking
Wang H, Perry J W, Lauring S A, Neddermann P, De Francesco R, Tai A W.
Gastroenterology, 2014 May;146(5):1373-85.

Why it is so difficult to develop an HCV preventive vaccine
Zingaretti C, De Francesco R, Abrignani S.
Clinical Microbiology and Infection, 2014 May;20 Suppl 5:103-9.

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