Publications 2016

Reverse plasticity: TGF- β and IL-6 induce Th1-to-Th17-cell transdifferentiation in the gut
Geginat J, Paroni M, Kastirr I, Larghi P, Pagani M, Abrignani S.
Eur. J. Immunol. 2016. 46: 2306–2310

Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy.
Paroni M, Magarotto A, Tartari S, Nizzoli G, Larghi P, Ercoli G, Gianelli U, Pagani M, Elli L, Abrignani S, Conte D, Geginat, Caprioli F.
NClin Transl Gastroenterol. 2016 Jul 14;7(7):e182. doi: 10.1038/ctg.2016.41.

A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, Berno V, Rossi RL, Reinbold R, Endele M, Schroeder T, Rocchigiani M, Szkarłat Ż, Oliviero S, Dalton S, Zippo A.
Nat Commun. 2016 Jun 15;7:11903.

The adipose mesenchymal stem cell secretome inhibits inflammatory responses of microglia: evidence for an involvement of sphingosine-1-phosphate signalling
Marfia G, Navone SE, Abdel Hadi L, Paroni M, Berno V, Beretta M, Gualtierotti R, Ingegnoli F, Levi V, Miozzo M, Geginat J, Fassina L, Rampini P, Tremolada C, Riboni L, Campanella R.
Stem Cells Dev. 2016 May 23. [Epub ahead of print]

IL-10 promotes homeostatic proliferation of human CD8+ memory T cells and, when produced by CD1c+ DCs, shapes naive CD8+ T-cell priming.
Nizzoli G, Larghi P, Paroni M, Crosti MC, Moro M, Neddermann P, Caprioli F, Pagani M, De Francesco R, Abrignani S, Geginat J.
Eur J Immunol. 2016 Apr 30. doi: 10.1002/eji.201546136. [Epub ahead of print]

Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema.
Protti A1, Maraffi T, Milesi M, Votta E, Santini A, Pugni P, Andreis DT, Nicosia F, Zannin E, Gatti S, Vaira V, Ferrero S, Gattinoni L.
Crit Care Med. 2016 Apr 6. [Epub ahead of print]

The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer.
Geginat J, Larghi P, Paroni M, Nizzoli G, Penatti A, Pagani M, Gagliani N, Meroni P, Abrignani S, Flavell RA.
Cytokine Growth Factor Rev. 2016 Mar 8. pii: S1359-6101(16)30019-3. doi:10.1016/j.cytogfr.2016.02.003. [Epub ahead of print]

Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T-cell acute lymphoblastic leukemia.
Jost TR, Borga C, Radaelli E, Romagnani A, Perruzza L, Omodho L, Cazzaniga G, Biondi A, Indraccolo S, Thelen M, Te Kronnie G, Grassi F.
J Leukoc Biol. 2016 Mar 1. pii: jlb.5MA0915-394R. [Epub ahead of print]

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.
Rigoni R, Fontana E, Guglielmetti S, Fosso B, D’Erchia AM, Maina V, Taverniti V, Castiello MC, Mantero S, Pacchiana G, Musio S, Pedotti R, Selmi C, Mora JR, Pesole G, Vezzoni P, Poliani PL, Grassi F, Villa A, Cassani B.
J Exp Med. 2016 Mar 7;213(3):355-75. doi: 10.1084/jem.20151116. Epub 2016 Feb 29.

Ectonucleotidase activity and immunosuppression in astrocyte-CD4 T cell bidirectional signaling.
Filipello F, Pozzi D, Proietti M, Romagnani A, Mazzitelli S, Matteoli M, Verderio C, Grassi F.
Oncotarget. 2016 Feb 2;7(5):5143-56. doi: 10.18632/oncotarget.6914.

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