Publications 2011

Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection
Marabita, F., Aghemo, A., De Nicola, S., Rumi, M. G., Cheroni, C., Scavelli, R., Crimi, M., Soffredini, R., Abrignani, S., De Francesco, R., and Colombo, M.
Hepatology
. 2011 Oct;54(4):1127-34.

Surface interactome in Streptococcus pyogenes
Galeotti CL, Bove E, Pezzicoli A, Nogarotto R, Norais N, Pileri S, Lelli B, Falugi F, Balloni S, Tedde V, Chiarot E, Bombaci M, Soriani M, Bracci L, Grandi G, Grifantini R.
Molecular and  Cellular Proteomics
. 2012 Apr;11(4):M111.015206. 

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naïve state in CD4 + T cells by the microRNA miR-125b
Rossi RL., Rossetti G., Wenandy L., Curti S., Ripamonti A., Bonnal RJP., Sciarretta BR., Moro M., Crosti MC., Gruarin P., Maglie S., Marabita F., Mascheroni D., Parente V., Comelli M., Trabucchi E., De Francesco R., Geginat J., Abrignani S., Pagani M.
Nature Immunol.
2011 Jun 26;12(8):796-803.

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output
Celona B., Weiner A., Di Felice F., Mancuso FM., Cesarini E., Rossi RL., Gregory L., Baban D., Rossetti G., Grianti P., Pagani M., Bonaldi T., Ragoussis J., Friedman N., Camilloni G., Bianchi ME., Agresti A.
PLoS Biol.
  2011 Jun;9(6).

Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells
Steinfelder S, Floess S, Engelbert D, Haeringer B, Baron U, Rivino L, Steckel B, Gruetzkau A, Olek S, Geginat J*, Huehn J*, Hamann A.*
*equal contributions
Blood.
2011 Mar 10;117(10):2839-46.

Dual role of anti-TNF therapy: enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues.
Bosè F, Raeli L, Garutti C, Frigerio E, Cozzi A, Crimi M, Caprioli F, Scavelli R, Altomare G, Geginat J, Abrignani S, Reali E.
Clin Immunol.
2011 May; 139(2):164-76. 

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins
Grifantini R, Pagani M, Pierleoni A, Grandi A, Parri M, Campagnoli S, Pileri P, Cattaneo D, Canidio E, Pontillo A, De Camilli E, Bresciani A, Marinoni F, Pedrazzoli E, Nogarotto R, Abrignani S, Viale G, Sarmientos P, Grandi G.
J. Proteomics.
2011, Dec 21; 75(2): 532-47. 

Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains
Stamataki Z, Coates S, Abrignani S, Houghton M, McKeating JA.
J Infect Dis.
  2011 Sep 1; 204(5):811-3. 

A high-resolution anatomical atlas of the transcriptome in the mouse embryo
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dolle P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A.
PLoS Biol
. 2011 Jan 18; 9(1).

Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase
Narjes F, Crescenzi B, Ferrara M, Habermann J, Colarusso S, Del Rosario Rico Ferreira M, Stansfield I, Mackay AC, Conte I, Ercolani C, Zaramella S, Palumbi MC, Meuleman P, Leroux-Roels G, Giuliano C, Fiore F, Di Marco S, Baiocco P, Koch U, Migliaccio G, Altamura S, Laufer R, De Francesco R, Rowley M.
J Med Chem
. 2011 Jan 13;54(1):289-301.

INGM researches are supported by