Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development.
Russo A, Gatti G, Alfieri R, Pesce E, Soanes K, Ricciardi S, Mancino M, Cheroni C, Vaccari T, Biffo S, Calamita P.
Dev Biol. 2019 Nov 1;455(1):100-111.

SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, Belli R, Taverna S, Andreazzoli M, Zippo A, Broccoli V.
Neuron. 2019 Sep 9. pii: S0896-6273(19)30639-7.

Dynamic and Cell-Specific DACH1 Expression in Human Neocortical and Striatal Development.
Castiglioni V, Faedo A, Onorati M, Bocchi VD, Li Z, Iennaco R, Vuono R, Bulfamante GP, Muzio L, Martino G, Sestan N, Barker RA, Cattaneo E.
Cereb Cortex. 2019 May 1;29(5):2115-2124.

Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India.
Fakiola M, Singh OP, Syn G, Singh T, Singh B, Chakravarty J, Sundar S, Blackwell JM.
PLoS Negl Trop Dis. 2019 Aug 16;13(8)

Sharing Programming Resources Between Bio* Projects.
Bonnal RJP, Yates A, Goto N, Gautier L, Willis S, Fields C, Katayama T, Prins P.
Methods Mol Biol. 2019;1910:747-766.

Enrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7-/- mice.
Perruzza L, Strati F, Gargari G, D’Erchia AM, Fosso B, Pesole G, Guglielmetti S, Grassi F.
Sci Rep. 2019 Jun 27;9(1):9315.

Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development.
Russo A, Gatti G, Alfieri R, Pesce E, Soanes K, Ricciardi S, Mancino M, Cheroni C, Vaccari T, Biffo S, Calamita P.
Dev Biol. 2019 Jul 5. pii: S0012-1606(18)30796-6.

TNF-Stimulated Gene-6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells.
Romano B, Elangovan S, Erreni M, Sala E, Petti L, Kunderfranco P, Massimino L, Restelli S,3, Sinha S, Lucchetti D, Anselmo A, Colombo FS, Stravalaci M, Arena V, D’Alessio S, Ungaro F, Inforzato A, Izzo AA, Sgambato A, Day AJ, Vetrano S.
Stem Cells. 2019; doi: 10.1002/stem.3010. [Epub ahead of print]

Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage.
Poli A, Zaurito AE, Abdul-Hamid S, Fiume R, Faenza I, Divecha N.
Int J Mol Sci. 2019 Apr 27;20(9).

FOXP1 circular RNA sustains mesenchymal stem cell identity via microRNA inhibition.
Cherubini A, Barilani M, Rossi RL, Jalal MMK, Rusconi F, Buono G, Ragni E, Cantarella G, Simpson HARW, Péault B, Lazzari L.
Nucleic Acids Res. 2019 Jun 4;47(10):5325-5340.

Allele-specific silencing as treatment for gene duplication disorders: proof-of-principle in autosomal dominant leukodystrophy.
Giorgio E, Lorenzati M, Rivetti di Val Cervo P, Brussino A, Cernigoj M, Della Sala E, Bartoletti Stella A, Ferrero M, Caiazzo M, Capellari S, Cortelli P, Conti L, Cattaneo E, Buffo A, Brusco A.
Brain. 2019 May 29. pii: awz139. [Epub ahead of print]

Pathologic up-regulation of TNFSF15-TNFRSF25 axis sustains endothelial dysfunction in unprovoked venous thromboembolism.
Bella SD, Calcaterra F, Bacci M, Carenza C, Pandolfo C, Ferrazzi P, Uva P, Pagani M, Lodigiani C, Mavilio D.
Cardiovasc Res. 2019 May 28. pii: cvz131. doi: 10.1093/cvr/cvz131. [Epub ahead of print]

4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in Facioscapulohumeral muscular dystrophy
Cortesi A, Pesant M, Sinha S, Marasca M, Sala E, Gregoretti F, Antonelli L, Oliva G, Chiereghin C, Soldà G, Bodega B*.
Genome Res. 2019 May 16. pii: gr.233288.117. doi: 10.1101/gr.233288.117. [Epub ahead of print]

Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington’s Disease
Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, Sogne E, Falqui A, Petricca L, Verani M, Martufi P, Caricasole A, Bresciani A, Cecchetti O, Rivetti di Val Cervo P, Sancini G, Riess O, Nguyen H, Seipold L, Saftig P, Biella G, Cattaneo and Zuccato C.
Journal of Clinical Investigation 2019 May 6; 130. pii: 120616. doi: 10.1172/JCI120616. [in press]

Novel biomarkers for Primary Biliary Cholangitis to improve diagnosis and understand underlying regulatory mechanisms.
Bombaci M, Pesce E, Torri A, Carpi D, Crosti M, Lanzafame M, Cordiglieri C, Sinisi A, Moro M, Bernuzzi F, Gerussi A, Geginat J, Muratori L, Terracciano LM, Invernizzi P, Abrignani S, Grifantini R.
Liver Int. 2019 Apr 29. doi: 10.1111/liv.14128. [Epub ahead of print]

Chromium 10× Single-Cell 3′ mRNA Sequencing of Tumor-Infiltrating Lymphocytes
De Simone M, Rossetti G, Pagani M.
Methods Mol Biol. 2019;1979:87-110.

Computation and Selection of Optimal Biomarker Combinations by Integrative ROC Analysis Using CombiROC.
Bombaci M, Rossi RL.
Methods Mol Biol. (2019);1959:247-259.

Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease.
Pelusi S, Baselli G, Pietrelli A, Dongiovanni P, Donati B, McCain MV, Meroni M, Fracanzani AL, Romagnoli R, Petta S, Grieco A, Miele L, Soardo G, Bugianesi E, Fargion S, Aghemo A, D’Ambrosio R, Xing C, Romeo S, De Francesco R, Reeves HL, Valenti LVC.
Sci Rep. 2019 Mar 6;9(1):3682.

A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes.
Bertolini I, Terrasi A, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Braidotti P, Todoerti K, Ferrero S, Caroli M, Ottobrini L, Vaccari T, Vaira V
EBioMedicine. 2019 Feb 5. pii: S2352-3964(19)30059-3. doi: 10.1016/j.ebiom.2019.01.051. [Epub ahead of print]

Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo.
Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Bosari S, Caroli M, Ottobrini L, Vaccari T, Vaira V.
EBioMedicine. 2019 Feb 5. pii: S2352-3964(19)30058-1. doi: 10.1016/j.ebiom.2019.01.052. [Epub ahead of print]

NIPBL: a new player in myeloid cells differentiation.
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A
Haematologica. 2019 Jan 10. pii: haematol.2018.200899. doi: 10.3324/haematol.2018.200899. [Epub ahead of print]

P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus.
Faliti CE, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, Pellegrini G, De Ponte Conti B, Rossi RL, Idzko M, Mazza EMC, Bicciato S, Traggiai E, Meroni PL, Grassi F
J Exp Med. 2019 Jan 17. pii: jem.20171976. doi: 10.1084/jem.20171976. [Epub ahead of print]

ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens.
Proietti M, Perruzza L, Scribano D, Pellegrini G, D’Antuono R, Strati F, Raffaelli M, Gonzalez SF, Thelen M, Hardt WD, Slack E, Nicoletti M, Grassi F.
Nat Commun. 2019 Jan 16;10(1):250.

INGM RESEARCH IS SUPPORTED BY