• GRUPPI DI RICERCA
  • Abrignani Lab
  • – Albanese Lab
  • Biffo Lab
  • – Manfrini Lab
  • Bodega Lab
  • – Marasca Lab
  • Cattaneo Lab
  • De Francesco Lab
  • Geginat Lab
  • Grifantini Lab
  • Lanzavecchia Lab
  • Lanzuolo Lab
  • Manganaro Lab
  • Montini Lab
  • Rizzello Lab
• PIATTAFORME
  • Bioinformatica
  • Citofluorimetria
  • Microscopia
  • Centro Organoidi
• PUBBLICAZIONI
  • Anno corrente
  • Archivio

• Modeling a biofluid-derived extracellular vesicle surface signature to differentiate pediatric idiopathic nephrotic syndrome clinical subgroups.
  Cricri G, Gobbini A, Bruno S, Bellucci L, Tassinari S, Caicci F, Tamburello C, Nittoli T, Paraboschi I, Berrettini A, Grifantini R, Bussolati B, Morello W, Montini G, Collino F.
  Sci Rep. 2024 Oct 28;14(1):25765.
• Typical NF2 and LTZR1 mutations are retained in an immortalized human schwann cell model of schwannomatosis
  Melfia V, Mohameda T, Colciagoa A, Fasciani A, De Francesco R, Bettio D, Cerqua C, Boaretto F, Basso E, Ferraresi S, Montini M, Eoli M, Papi L, Trevisson E, Magnaghi V.
  Heliyon 10 (2024) e38957.
• LINE1 modulate human T cell function by regulating protein synthesis during the life span.
  Burattin FV, Vadalà R, Panepuccia M, Ranzani V, Crosti M, Colombo FA, Ruberti C, Erba E, Prati D, Nittoli T, Montini G, Ronchi A, Pugni L, Mosca F, Ricciardi S, Abrignani S, Pietrasanta C, Marasca F, Bodega B.
  Sci Adv. 2024 Oct 11;10(41):eado2134.
• Primary HIV infection during chronic treatment with imatinib: impact on infection dynamics.
  Bozzi G, Centazzo M, Scaglioni S, Butta GM, Saltini P, Liparoti A, Trombetta E, Prati D, Gori A, Bandera A, Manganaro L.
  AIDS. 2024 Aug 1;38(10):1601-1604.
• Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination
  Fumagalli V, Ravà M, Marotta D, Di Lucia P, Bono E, Giustini L, De Leo F, Casalgrandi M, Monteleone E, Mouro V, Malpighi C, Perucchini C, Grillo M, De Palma S, Donnici L, Marchese S, Conti M, Muramatsu H, Perlman S, Pardi N, Kuka M, De Francesco E, Bianchi M, Guidotti L, Iannacone M
  Nat Immunol (2024).
• SARS-CoV-2: A Glance at the Innate Immune Response Elicited by Infection and Vaccination.
  Manfrini N, Notarbartolo S, Grifantini R, Pesce E.
  Antibodies (Basel). 2024 Feb 8;13(1):13
• Tracking the immune response profiles elicited by the BNT162b2 vaccine in COVID-19 unexperienced and experienced individuals.
  Galeota E, Bevilacqua V, Gobbini A, Gruarin P, Bombaci M, Pesce E, Favalli A, Lombardi A, Vincenti F, Ongaro J, Fabbris T, Curti S, Martinovic M, Toccafondi M, Lorenzo M, Critelli A, Clemente F, Crosti M, Sarnicola ML, Martinelli M, La Sala L, Espadas A, Donnici L, Borghi MO, De Feo T, De Francesco R, Prati D, Meroni PL, Notarbartolo S, Geginat J, Gori A, Bandera A, Abrignani S, Grifantini R.
  Clin Immunol. 2024 Feb 28;261:110164.
• Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein.
  D’Acunto E, Muzi A, Marchese S, Donnici L, Chiarini V, Bucci F, Pavoni E, Ferrara FF, Cappelletti M, Arriga R, Serrao SM, Peluzzi V, Principato E, Compagnone M, Pinto E, Luberto L, Stoppoloni D, Lahm A, Groß R, Seidel A, Wettstein L, Münch J, Goodhead A, Parisot J, De Francesco R, Ciliberto G, Marra E, Aurisicchio L, Roscilli G.
  Antibodies (Basel). 2024 Jan 5;13(1):5.
• Alemtuzumab-induced thyroid eye disease successfully treated with a single low-dose of rituximab
  Muller I, Maioli S, Armenti M, Porcaro L, Currò N, Iofrida E, Pignataro L, Manso J, Mian C, Geginat J, Salvi M.
  Eur Thyroid J. 2024 Mar 1:ETJ-23-0236.
• Identification of serum microRNAs associated with Lymphangioleiomyomatosis
  R. L. Rossi, D. Elia, O. Torre, R. Cassandro, A. Caminati, C. Vasco, E. Carelli, S. Abrignani, J. Geginat*, S. Harari.
  American Journal of Respiratory Cell and Molecular Biology (IF 6.4), 2024, 70(2):146-148.
• Characterization of human CD4+ EOMES+ GzmK+ T-cell subsets unveils an uncoupling of suppressive functions from IL-10-producing capacities.
  Pulvirenti N, Silvetri Y, Clemente F, Bosotti R, Carelli E, Moschetti G, Gruarin P, Vasco C, Crosti MC, Sarnicola ML, Valenti L, Prati D, Abrignani S, Geginat J.
  Eur J Immunol. 2024 Feb 23:e2350675.
• High-throughput peptide array analysis and computational techniques for serological profiling of flavivirus infections: Implications for diagnostics and vaccine development.
  Bombaci M, Fassi EMA, Gobbini A, Mileto D, Cassaniti I, Pesce E, Casali E, Mancon A, Sammartino J, Ferrari A, Percivalle E, Grande R, Marchisio E, Gismondo MR, Abrignani S, Baldanti F, Colombo G, Grifantini R.
  J Med Virol. 2024 Sep;96(9):e29923.
• Early-onset cancers: Biological bases and clinical implications.
  Mauri G, Patelli G, Sartore-Bianchi A, Abrignani S, Bodega B, Marsoni S, Costanzo V, Bachi A, Siena S, Bardelli A.
  Cell Rep Med. 2024 Sep 17;5(9):101737
• Protocol for the detection of defined T cell clones in a heterogeneous cell population
  Gobbini A, Bandera A, Grifantini R, Abrignani S, Notarbartolo S.
  STAR Protoc. 2024 Mar 15;5(1):102787.
• Identification of two autoantigens recognised by circulating autoantibodies as potential biomarkers for diagnosing giant cell arteritis.
  Pesce E, Bombaci M, Croci S, Bonacini M, Marvisi C, Ricordi C, Monti S, Muratore F, Abrignani S, Caporali R, Borghi MO, Salvarani C, Villiger PM, Grifantini R, Meroni PL.
  Clin Exp Rheumatol. 2024 Jul;42(7):1317-1320.
• Jingle Cell Rock: Steering Cellular Activity With Low-Intensity Pulsed Ultrasound (LIPUS) to Engineer Functional Tissues in Regenerative Medicine.
  Marcotulli M, Barbetta A, Scarpa E, Bini F, Marinozzi F, Ruocco G, Casciola CM, Scognamiglio C, Carugo D, Cidonio G.
  Ultrasound Med Biol. 2024 Sep 16:S0301-5629(24)00327-2.
• IRescue: uncertainty-aware quantification of transposable elements expression at single cell level.
  Polimeni B, Marasca F, Ranzani V, Bodega B.
  Nucleic Acids Res. 2024 Sep 13:gkae793.
• The crosstalk between metabolism and translation.
  Biffo S, Ruggero D, Santoro MM.
  Cell Metab. 2024 Sep 3;36(9):1945-1962.
• Unveiling Milan’s hidden cases of plague occurred in autumn 1629, before the great 1630 epidemic.
  Nodari R, Fois L, Luconi E, Vaglienti F, Comandatore F, Galli M.
  Infez Med. 2024 Sep 1;32(3):403-412.
• Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.
  Galimberti M, Nucera MR, Bocchi VD, Conforti P, Vezzoli E, Cereda M, Maffezzini C, Iennaco R, Scolz A, Falqui A, Cordiglieri C, Cremona M, Espuny-Camacho I, Faedo A, Felsenfeld DP, Vogt TF, Ranzani V, Zuccato C, Besusso D, Cattaneo E.
  Nat Commun. 2024 Aug 2;15(1):6534.
• Biochemical properties of chromatin domains define genome compartmentalization.
  Lucini F, Petrini C, Salviato E, Pal K, Rosti V, Gorini F, Santarelli P, Quadri R, Lembo G, Graziano G, Di Patrizio Soldateschi E, Tagliaferri I, Pinatel E, Sebestyén E, Rotta L, Gentile F, Vaira V, Lanzuolo C, Ferrari F.
  Nucleic Acids Res. 2024 Jul 8;52(12):e54.
• Ruthenium(II) Polypyridyl Complexes with Benzoxazole Derivatives and Non-Innocent Ligands as Effective Antioxidants in Human Neuroblasts.
  Giacomazzo GE, Conti L, Paderni D, Sfragano PS, Quadrini L, Macedi E, Andreini C, Donati C, Bernacchioni C, Mulas G, Valtancoli B, Palchetti I, Giorgi L, Fusi V, Cencetti F, Giorgi C.
  Chemistry. 2024 Jul 5;30(38):e202400834.
• Endothelial cellular senescence and tau accumulation: An interplay full of opportunities?
  Oliveri D, Moschetti G, Griego A, Scarpa E.
  Ibrain. 2024 May 9;10(2):225-230.
• A Versatile Pipeline for Analyzing Dynamic Changes in Nuclear Bodies in a Variety of Cell Types.
  Di Gioia V, Zamporlini J, Vadalà R, Parmigiani E, Bodega B, Marasca F.
  J Vis Exp. 2024 Jun 28;(208).
• The Paradox of Ribosomal Insufficiency Coupled with Increased Cancer: Shifting the Perspective from the Cancer Cell to the Microenvironment.
  D’Andrea G, Deroma G, Miluzio A, Biffo S.
  Cancers (Basel). 2024 Jun 28;16(13):2392.
• Genetic/epigenetic effects in NF1 microdeletion syndrome: beyond the haploinsufficiency, looking at the contribution of not deleted genes.
  Tritto V, Bettinaglio P, Mangano E, Cesaretti C, Marasca F, Castronovo C, Bordoni R, Battaglia C, Saletti V, Ranzani V, Bodega B, Eoli M, Natacci F, Riva P.
  Hum Genet. 2024 Jun;143(6):775-795.
• Chromatin plasticity in mechanotransduction.
  Vivo M, Rosti V, Cervone S, Lanzuolo C.
  Curr Opin Cell Biol. 2024 Jun;88:102376.
• Dissecting the Puzzling Roles of FAM46C: A Multifaceted Pan-Cancer Tumour Suppressor with Increasing Clinical Relevance.
  Lai G, De Grossi F, Catusi I, Pesce E, Manfrini N.
• Generation of human cerebral organoids with a structured outer subventricular zone.
  Walsh RM, Luongo R, Giacomelli E, Ciceri G, Rittenhouse C, Verrillo A, Galimberti M, Bocchi VD, Wu Y, Xu N, Mosole S, Muller J, Vezzoli E, Jungverdorben J, Zhou T, Barker RA, Cattaneo E, Studer L, Baggiolini A.
  Cell Rep. 2024 Apr 23;43(4):114031.
• Alemtuzumab-induced thyroid eye disease successfully treated with a single low dose of rituximab.
  Muller I, Maioli S, Armenti M, Porcaro L, Currò N, Iofrida E, Pignataro L, Manso J, Mian C, Geginat J, Salvi M.
  Eur Thyroid J. 2024 Apr 11;13(2):e230236.
  Cancers (Basel). 2024 Apr 27;16(9):1706.
• Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination.
  Fumagalli V, Ravà M, Marotta D, Di Lucia P, Bono EB, Giustini L, De Leo F, Casalgrandi M, Monteleone E, Mouro V, Malpighi C, Perucchini C, Grillo M, De Palma S, Donnici L, Marchese S, Conti M, Muramatsu H, Perlman S, Pardi N, Kuka M, De Francesco R, Bianchi ME, Guidotti LG, Iannacone M.
  Nat Immunol. 2024 Apr;25(4):633-643.
• Nanoscale myelinogenesis image in developing brain via super-resolution nanoscopy by near-infrared emissive curcumin-BODIPY derivatives.
  Chen J, Yu Y, Wang S, Shen Y, Tian Y, Rizzello L, Luo K, Tian X, Wang T, Xiong L.
  J Nanobiotechnology. 2024 Mar 11;22(1):106.
• SARS-CoV-2: A Glance at the Innate Immune Response Elicited by Infection and Vaccination.
  Manfrini N, Notarbartolo S, Grifantini R, Pesce E.
  Antibodies (Basel). 2024 Feb 8;13(1):13.
• The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant
  Oliveto S, Ritter P, Deroma G, Miluzio A, Cordiglieri C, Benvenuti MR, Mutti L, Raimondi MT, Biffo S.
  Mesothelioma Cells. Genes (Basel). 2024 Feb 1;15(2):199.
• ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota.
  Eberhart T, Stanley FU, Ricci L, Chirico T, Ferrarese R, Sisti S, Scagliola A, Baj A, Badurek S, Sommer A, Culp-Hill R, Dzieciatkowska M, Shokry E, Sumpton D, D’Alessandro A, Clementi N, Mancini N, Cardaci S.
  Cell Death Dis. 2024 Feb 1;15(2):105.
• Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein.
  D’Acunto E, Muzi A, Marchese S, Donnici L, Chiarini V, Bucci F, Pavoni E, Ferrara FF, Cappelletti M, Arriga R, Serrao SM, Peluzzi V, Principato E, Compagnone M, Pinto E, Luberto L, Stoppoloni D, Lahm A, Groß R, Seidel A, Wettstein L, Münch J, Goodhead A, Parisot J, De Francesco R, Ciliberto G, Marra E, Aurisicchio L, Roscilli G.
  Antibodies (Basel). 2024 Jan 5;13(1):5.
• Leveraging Tissue-Specific Enhancer-Target Gene Regulatory Networks Identifies Enhancer Somatic Mutations That Functionally Impact Lung Cancer.
  Hariprakash JM, Salviato E, La Mastra F, Sebestyén E, Tagliaferri I, Silva RS, Lucini F, Farina L, Cinquanta M, Rancati I, Riboni M, Minardi SP, Roz L, Gorini F, Lanzuolo C, Casola S, Ferrari F.
  Cancer Res. 2024 Jan 2;84(1):133-153.
• Chromatin organization of muscle stem cell.
  Santarelli P, Rosti V, Vivo M, Lanzuolo C.
  Curr Top Dev Biol. 2024;158:375-406.
• The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell division.
  Degiacomi G, Chiarelli LR, Riabova O, Loré NI, Muñoz-Muñoz L, Recchia D, Stelitano G, Postiglione U, Saliu F, Griego A, Scoffone VC, Kazakova E, Scarpa E, Ezquerra-Aznárez JM, Stamilla A, Buroni S, Tortoli E, Rizzello L, Sassera D, Ramón-García S, Cirillo DM, Makarov V, Pasca MR.
• Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
  Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa PE, Rodighiero S, Gavilán E, Romanenghi M, Duso BA, Bonetti E, Manganaro L, Pallavi R, Trastulli D, Pallavicini I, Gentile C, Monzani S, Leonardi T, Pasqualato S, Buttinelli G, Di Martino A, Fedele G, Schiavoni I, Stefanelli P, Meroni G, de Francesco R, Steinkuhler C, Fossati G, Iannacone M, Minucci S, Pelicci PG.
  Sci Signal. 2023 Dec 19;16(816):eade0326.
• SARS-COV-2 specific t-cells in patients with thyroid disorders related to COVID-19 are enriched in the thyroid and acquire a tissue-resident memory phenotype.
  Silvestri Y, Clemente F, Moschetti G, Maioli S, Carelli E, Espadas de Arias A, Torelli R, Longhi E, De Feo T, Crosti M, Sarnicola ML, Salvi M, Mantovani G, Arosio M, Bombaci M, Pesce E, Grifantini R, Abrignani S, Geginat J, Muller I.
  Clin Immunol. 2023 Sep;254:109684.
• Brain cholesterol therapy for Huntington’s disease – Does it make sense?
  Cattaneo E, Barker RA.
  Clin Transl Med. 2024 Jul;14(7):e1746. doi: 10.1002/ctm2.1746.
• Neuroprotection by ADAM10 inhibition requires TrkB signaling in the Huntington’s disease hippocampus.
  Scolz A, Vezzoli E, Villa M, Talpo F, Cazzola J, Raffin F, Cordiglieri C, Falqui A, Pepe G, Maglione V, Besusso D, Biella G, Zuccato C.
  Cell Mol Life Sci. 2024 Aug 7;81(1):333.
  Int J Antimicrob Agents. 2024 Jul 26;64(4):107278.
• High-throughput peptide array analysis and computational techniques for serological profiling of flavivirus infections: Implications for diagnostics and vaccine development.
  Bombaci M, Fassi EMA, Gobbini A, Mileto D, Cassaniti I, Pesce E, Casali E, Mancon A, Sammartino J, Ferrari A, Percivalle E, Grande R, Marchisio E, Gismondo MR, Abrignani S, Baldanti F, Colombo G, Grifantini R.
  J Med Virol. 2024 Sep;96(9):e29923.
• Early-onset cancers: Biological bases and clinical implications.
  Mauri G, Patelli G, Sartore-Bianchi A, Abrignani S, Bodega B, Marsoni S, Costanzo V, Bachi A, Siena S, Bardelli A.
  Cell Rep Med. 2024 Sep 17;5(9):101737.
• CancerHubs: a systematic data mining and elaboration approach for identifying novel cancer-related protein interaction hubs.
  Ferrari I, De Grossi F, Lai G, Oliveto S, Deroma G, Biffo S, Manfrini N.
  Brief Bioinform. 2024 Nov 22;26(1):bbae635.

INGM RESEARCH IS SUPPORTED BY